CCR3 antagonist 1

製品番号: HY-U00331 純度: 99.90%: Data Sheet SDS COA 取扱説明書
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CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

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CCR3 antagonist 1 構造式

CAS 番号 : 879399-82-3

容量	価格（税別）	在庫状況	数量
5 mg	$425	在庫あり	Estimated Time of Arrival: December 31
10 mg	$650	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

顧客検証

•Bioact Mater. 2021 Jan 7;6(7):2039-2057. [Abstract]

CCR アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.

IC₅₀ & Target^[1]

CCR3

分子量

490.42

分子式

C₁₉H₂₁Cl₂N₃O₄S₂

CAS 番号

879399-82-3

Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(O)CC1=CSC(SCC(NC[C@H]2CN(CC3=CC=C(Cl)C(Cl)=C3)CCO2)=O)=N1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶剤 & 溶解度

体外:

DMSO : 125 mg/mL (254.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0391 mL	10.1953 mL	20.3907 mL
5 mM	0.4078 mL	2.0391 mL	4.0781 mL
10 mM	0.2039 mL	1.0195 mL	2.0391 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.90%

Select Batch:

データシート (267 KB) SDS (252 KB)

COA (244 KB) HNMR (263 KB) LCMS (87 KB)

取扱説明書 (2659 KB)

参考文献

[1]. MORPHOLINE COMPOUND. WO 2006028284 A1

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0391 mL	10.1953 mL	20.3907 mL	50.9767 mL
	5 mM	0.4078 mL	2.0391 mL	4.0781 mL	10.1953 mL
	10 mM	0.2039 mL	1.0195 mL	2.0391 mL	5.0977 mL
	15 mM	0.1359 mL	0.6797 mL	1.3594 mL	3.3984 mL
	20 mM	0.1020 mL	0.5098 mL	1.0195 mL	2.5488 mL
	25 mM	0.0816 mL	0.4078 mL	0.8156 mL	2.0391 mL
	30 mM	0.0680 mL	0.3398 mL	0.6797 mL	1.6992 mL
	40 mM	0.0510 mL	0.2549 mL	0.5098 mL	1.2744 mL
	50 mM	0.0408 mL	0.2039 mL	0.4078 mL	1.0195 mL
	60 mM	0.0340 mL	0.1699 mL	0.3398 mL	0.8496 mL
	80 mM	0.0255 mL	0.1274 mL	0.2549 mL	0.6372 mL
	100 mM	0.0204 mL	0.1020 mL	0.2039 mL	0.5098 mL